ul. M. Sklodowskiej-Curie 24A
15-276 Bialystok
phone/fax: (85) 746 86 01
e-mail: alergol@amb.edu.pl

Senior assistants:

• Dr. Krzysztof W. Kowal
  board certified in internal medicine, allergologist
• Dr. Ziemowit Zietkowski
  board certified in internal medicine, allergologist
• Dr. Irena Alina Złotnik
  board certified in internal medicine, allergologist
• Dr. Izabela Kemona-Chetnik
  board certified in internal medicine
• Dr. Iwona Kucharewicz
  board certified in internal medicine

  Assistants:

• Dr. Marcin Moniuszko
• Dr. Maria Magdalena Tomasiak-Lozowska
• Dr. Sebastian Zukowski

  Ward sister:

• Jadwiga Dudzik
  spec. nursing behaviour

• Diagnostics and treatment of allergic diseases especially bronchial asthma
• Recognise and treatment chronic obstructive pulmonum disease (COPD)
• Qualifications and performing of specific immunotherapy
• Diagnostic and a causal treatment of Hymenoptera venom allergy venom immunotherapy (VIT)
• Diagnostics of the professional and drug allergy
• Services of bronchoscope with BAL, rhinomanometry and spirometry
• Diagnostic and treatment of other internal diseases
• Prophylactic of the allergic diseases

• Teaching of internal medicine and allergology to the students of medical faculty, postgraduate training in internal medicine and allergology
• Organising of the teaching courses (CMKP) in the field of allergology

• Research of asthma pathomechanisms (cytokines, HR-test, leukotrienes, exercise induced asthma)
• Bronchial hyper-reactivity - mechanisms and methods of evaluation
• The specific immunotherapy - mechanisms and the reason of failure
• Pathomechanisms of the pseudo-allergic reactions

• The significant decrease of asthma death and moderate of their exacerbations.
• Diagnostic and therapeutic bronchifiberoscopy including BAL
• Venom immunotherapy (VIT) "rush" and "ultra rush" method with the evaluation of efficacy by challenge test
• IL-13 in nasal lavage after allergen provocation test was detect. Recombinant IL-10 inhibits pro-inflammatory cytokine release less in non-atopic than in atopic patients
• Decrease in specific bronchial reactivity was noted in atopic patients sensitive to mites after several years of specific immunotherapy
• The leukotriens can participate in pseudo-allergic reactions after insect sting

• Kucharewicz I., Kasacka I., Pawlak D., Tankiewicz-Kwedlo A., Mroczko B., Buczko B., Bodzenta-Łukaszyk A.: The concentration of kynurenine in rat model of asthma. Folia Histochemica et Cytobiologica 2008; vol. 46 no. 2: pp. 199-203.
• Ziętkowski Z., Skiepko R., Tomasiak M.M., Bodzenta-Łukaszyk A.: Soluble CD40 Ligand and Soluble P-Selectin in Allergic Asthma Patients During Exercise-Induced Bronchoconstriction. J. Investig Allergol Clin. Immunol. 2008; vol. 18(4): 272-278.
• Ziętkowski Z., Tomasiak M.M., Skiepko R., Bodzenta-Łukaszyk A.: RANTES in exhaled breath condensate of stable and unstable asthma patients. Respiratory Medicine 2008; 102: 1198-1202.
• Kowal K., Bodzenta-Łukaszyk A., Pampuch A., Szmitkowski M., Żukowski S., Benedetta Donati M., Iacoviello L.: Analysis of -675 4G/5G SERPINE1 and C-159T CD14 Polymorphisms in House Dust Mite-Allergic Asthma Patients.
  J. Investig Allergol Clin. Immunol. 2008; vol. 18(4): 284-292.
• Kucharewicz I., Mogielnicki A., Kasacka I., Buczko W., Bodzenta-Łukaszyk A.: Plasmin System Regulation in an Ovalbumin-Induced Rat Model of Asthma. Int Arch Allergy Immunol 2008; 147: 190-196.
• Kowal K., Żukowski S., Moniuszko M., Bodzenta-Łukaszyk A.: Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients. Folia Histochemica et Cytobiologica 2008; vol. 46 no. 2: pp. 193-198.
• Ziętkowski Z., Skiepko R., Tomasiak M.M., Bodzenta-Łukaszyk A.: Endothelin-1 in exhaled breath condensate of stable and unstable asthma patients. Respiratory Medicine 2008; 102: 470-474.
• Moniuszko M., Kowal K., Żukowski S., Dąbrowska M., Bodzenta-Łukaszyk A.: Frequencies of circulating CD4+CD25+CD127 low cells in atopics are altered by bronchial allergen challenge. European Journal of Clinical Investigation 2008; 38 (3): 201-204.
• Tomasiak M.M., Tomasiak M., Ziętkowski Z., Skiepko R., Bodzenta-Łukaszyk A.: N-Acetyl-Beta-Hexosaminidase Activity in Asthma. Int Arch Allergy Immunol 2008; 146: 133-137.
• Moniuszko M., Bodzenta-Łukaszyk A., Kowal K., Dąbrowska M.: Bronchial macrophages in asthmatics reveal decreased CD16 expression and substantial levels of receptors for IL-10, but not IL-4 and IL-7. Folia histochemica et cytobiologica 2007; vol. 45, no. 3: 181-189.
• Kucharewicz I., Kemona-Chętnik I., Reduta T., Wierzbicka I., Flisiak R., Bodzenta-Łukaszyk A.: Drug rash with eosinophilia and systemic symptoms after Ibuprofen intake. J. Investig Allergol Clin. Immunol 2007; vol. 17(5): 345-349.
• Kowal K., Bodzenta-Łukaszyk A., Pampuch A., Szmitkowski M., Donati M.B., Iacoviello L.: Plasminogen activator inhibitor-1 plasma concentration in allergic asthma patients during allergen challenge. Int Arch Allergy Immunol. 2007; 144: 240-246.
• Ziętkowski Z., Bodzenta-Łukaszyk A., Tomasiak M.M., Skiepko R., Szmitkowski M., Mroczko B.: The Role of Endothelium-Derived Mediators in Exercise-Induced Bronchoconstriction. Int Arch Allergy Immunol. 2007 Mar 14; 143(4): 299-310.
• Kucharewicz I., Bodzenta-Łukaszyk A., Szymański W., Mroczko B., Szmitkowski M.: Basal serum tryptase level correlates with severity of Hymenoptera sting and age. J Investig Allergol Clin Immunol. 2007; 17(2) : 65-69.
• Kemona-Chętnik I., Bodzenta-Łukaszyk A., Butkiewicz A., Dymnicka-Piekarska W., Kemona H.: Trombocytopoeza u chorych z astmą alergiczną. Polskie Archiwum Medycyny Wewnętrznej 2007; 117(1-2): 9-13.